New Step by Step Map For cees dekker
New Step by Step Map For cees dekker
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‘Certainly, which is about suitable. I hunt for a Actual physical understanding of biological units inside a base-up way. I do think you can distinguish 3 strains of research in my group for the time being. The 1st concerns chromosome construction: How will you receive a metre-prolonged DNA polymer folded and organised in this kind of microscopic mobile? We have produced visualisation approaches that allow us to study how, as an example, SMC proteins loop DNA (movie on Youtube) so that you can Develop up chromosomes.
It was only during the nineties nevertheless, when nanotechnology had Highly developed to some amount exactly where one molecules might be manipulated, that the 1st experimental devices started to look.
Around the exact time, the team of Paul McEuen, who was then based mostly with the University of California, Berkeley, showed related effects on ropes of bundled nanotubes. With regards to the wrapping angle, nanotubes can can be found in metallic or semiconducting variants, a prediction that we and Charles Lieber’s group at Harvard College independently verified working with scanning tunnelling spectroscopy experiments.
A rhythmically pulsing leaf-spring DNA-origami nanoengine that drives a passive follower Mathias Centola
Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond intelligent structure in 2005. (nl)
Immediate immobilization of native yeast iso-one cytochrome c on bare gold: quick electron relay to redox enzymes and zeptomole protein-movie voltammetry
You're a Christian. If you may make this kind of synthetic mobile, would you be one particular stage nearer to God, or would the part of God have diminished somewhat yet again?
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‘The fantastically delicate way during which components in mother nature purpose under no circumstances ceases to amaze me. If we fix the puzzle of how existence came into remaining, I be expecting that my amazement with the complexity of creation will have greater and with it my awe to the greatness in the Creator.’
Instance (4) of bending configurations in 3D simulations of DNA rods on nanopores. A percentage of the membrane is revealed in grey, the rim from the pore is highlighted in red, in addition to a 3D rendering with the movement from the DNA rod is displayed.
Cees ceesdekker.net Dekker is Distinguished University Professor at TU Delft. Educated as being a physicist, he pioneered nanotechnology with several discoveries on carbon nanotubes inside the nineties. Given that 2000, he moved to single-molecule biophysics and nanobiology. His present analysis focuses on (i) nanopores for protein sequencing; (ii) chromosome structure, in particular SMC motor protein; and (iii) developing a dwelling synthetic cell from lifeless molecules. Dekker is definitely an elected member from the KNAW and fellow to the APS and the IOP.
2008, very first observation of protein-coated DNA translocation by way of nanopores; solved the origin in the electrophoretic power on DNA in nanopores; identified a substantial velocity improve of microtubules in electric fields; found an anomalous electro-hydrodynamic orientation of microtubules; and resolved the origin of sounds in carbon nanotubes in liquid
2013, managed shaping of Reside bacterial cells into arbitrary designs; and discovery of spontaneous fluctuations during the handedness of histone tetrasomes